{ "@context": "http://iiif.io/api/presentation/3/context.json", "id": "https://digital.middlesexcollege.edu/iiif/manifest/AA00002413/00001", "type": "Manifest", "label": { "none": [ "Cheminformatics and Bioinformatics of Diverse Roles of Fe (II) \u0026 Fe (III) in Biomolecules" ] }, "metadata": [ { "label": { "en": [ "Abstract" ] }, "value": { "none": [ "Metals play diverse roles in the biological system. Several transitional metals have been reported to play important roles in the biological process; however, the enzymatic activities performed by Fe (II) and Fe (III) metal centers with octahedron geometry are presented in this research. The metal Fe in proteins was found perform the following enzymatic activities; oxidoreductase, transferase, hydrolase, lyase, and isomerase. Moreover, in the enzyme class of ligase, Fe (II) or Fe (III) was not in in proteins performing ligase activities. To conduct this study, the aid of web databases was predominant. Brenda, MetalPDB, RCSB, Uniprot, and PubMed were explored to find particularly important information about the biochemicals roles of the Metallo proteins encompassing Fe as the active Metal centers. It was found that in the oxidoreductase activities only Fe (II) in octahedral geometry is only used to perform this enzymatic activity. For transferase hydrolase activities, Fe (II) and (III) with whether histidine or heme ligand is used to perform the same transferase activity. For hydrolase activities, both Fe (II) \u0026 (III) are used to perform hydrolase activities. For Lyase, when a protein uses Fe (III) as an active center it uses neither histidine nor heme. For isomerase, only one protein was found having Fe (II) as the metal center. For the ligase activities, there were no proteins utilizing octahedral Fe centers to perform this activity." ] } }, { "label": { "en": [ "Publication Date" ] }, "value": { "none": [ "2020" ] } }, { "label": { "en": [ "Hierarchical Spatial" ] }, "value": { "none": [ "New Jersey -- Edison" ] } }, { "label": { "en": [ "Holding Location" ] }, "value": { "none": [ "Middlesex County College Institution" ] } }, { "label": { "en": [ "Permanent Link" ] }, "value": { "none": [ "http://middlesexcc.sobeklibrary.com/AA00002413/00001" ] } }, { "label": { "en": [ "Creator" ] }, "value": { "none": [ "Gomez, Mauricio, Jr.", "Middlesex College Department of Natural Sciences", "Ghosh, Phalguni" ] } }, { "label": { "en": [ "Publisher" ] }, "value": { "none": [ "Middlesex College" ] } }, { "label": { "en": [ "Place of Publication" ] }, "value": { "none": [ "Edison, NJ" ] } }, { "label": { "en": [ "Type" ] }, "value": { "none": [ "Mixed Material" ] } }, { "label": { "en": [ "Source Institution" ] }, "value": { "none": [ "Middlesex County College Institution" ] } }, { "label": { "en": [ "Subjects / Keywords" ] }, "value": { "none": [ "College students -- poster presentations", "Student Works -- Natural Sciences -- poster presentations", "Chemistry", "Biochemistry", "Middlesex College (Edison, NJ) -- Student works", "Middlesex County College (Edison, NJ)" ] } }, { "label": { "en": [ "Temporal Coverage" ] }, "value": { "none": [ "Academic Year 2020-2021 ( 2020 - 2021 )" ] } }, { "label": { "en": [ "Title" ] }, "value": { "none": [ "Cheminformatics and Bioinformatics of Diverse Roles of Fe (II) \u0026 Fe (III) in Biomolecules" ] } }, { "label": { "en": [ "Abbreviated Title" ] }, "value": { "none": [ "Student Symposium 2020" ] } }, { "label": { "en": [ "Format" ] }, "value": { "none": [ "Mixed Material" ] } }, { "label": { "en": [ "Digital Resource Creation Date" ] }, "value": { "none": [ "6/14/2021" ] } } ], "service": [ { "@context": "http://iiif.io/api/search/2/context.json", "id": "https://digital.middlesexcollege.edu/iiif/manifest/AA00002413/00001/search", "type": "SearchService2", "profile": "http://iiif.io/api/search/2/search" } ], "seeAlso": [ { "id": "https://digital.middlesexcc.edu/content/AA/00/00/24/13/00001/AA00002413_00001.mets.xml", "type": "Dataset", "format": "application/mets\u002Bxml", "label": { "en": "METS" } }, { "id": "https://digital.middlesexcc.edu/content/AA/00/00/24/13/00001/marc.xml", "type": "Dataset", "format": "application/marcxml\u002Bxml", "label": { "en": "MARCXML" } } ], "items": [] }