{ "@context": "http://iiif.io/api/presentation/3/context.json", "id": "https://digital.middlesexcollege.edu/iiif/manifest/AA00002430/00001", "type": "Manifest", "label": { "none": [ "Amine-Catalyzed Direct Asymmetric Mannich Reaction" ] }, "metadata": [ { "label": { "en": [ "Abstract" ] }, "value": { "none": [ "We explored the natural amino acid L-proline to be catalysts for the direct asymmetric Mannich-type reaction of acetone with a variety of preformed aldimines derived from o-anisidine. In the first part of this project, we explored the direct asymmetric Mannich-type reaction between acetone and N-(p-nitrobenzylidene)Aniline, in the presence of 30 mol % of L-proline.N-(p-nitrobenzylidene)Aniline was the intermediate compound which made between Aniline and 4-nitrobenzaldehyde.The reaction was set under normal condition and room temperature. We got 2 conformation products. Detail characterization of two products was determined by TLC, Column Chromatography, NMR, and HPLC. The percent yield of main product was 67.5%, and the published value was 52%. In the second part of this project, we explored the same asymmetric Mannich-type reaction using p-Anisaldehyde instead of 4-nitrobenzaldehyde. We got an unknown compound, and we could not identify the structure of this compound until we get mass spectrum. In the third part of this project, we explored one-pot three-component reaction between acetone, Aniline, and p-Anisaldehyde in the presence of 30 mol % of L-proline. We got 2 conformation products too, but the ratio of major and minor conformers is switched." ] } }, { "label": { "en": [ "Publication Date" ] }, "value": { "none": [ "2015 December 23" ] } }, { "label": { "en": [ "Hierarchical Spatial" ] }, "value": { "none": [ "New Jersey -- Edison" ] } }, { "label": { "en": [ "Holding Location" ] }, "value": { "none": [ "Middlesex County College Institution" ] } }, { "label": { "en": [ "Permanent Link" ] }, "value": { "none": [ "http://middlesexcc.sobeklibrary.com/AA00002430/00001" ] } }, { "label": { "en": [ "Creator" ] }, "value": { "none": [ "Zhang, Xiaoqiao (Kerry Zhang)", "Ghosh, Phalguni", "Lavey, Brian", "Middlesex College, Department of Natural Sciences" ] } }, { "label": { "en": [ "Publisher" ] }, "value": { "none": [ "Middlesex College" ] } }, { "label": { "en": [ "Place of Publication" ] }, "value": { "none": [ "Edison, NJ" ] } }, { "label": { "en": [ "Type" ] }, "value": { "none": [ "Mixed Material" ] } }, { "label": { "en": [ "Source Institution" ] }, "value": { "none": [ "Middlesex County College Institution" ] } }, { "label": { "en": [ "Subjects / Keywords" ] }, "value": { "none": [ "College students -- poster presentations", "Student Works -- Natural Sciences -- poster presentations", "Chemistry", "Student works -- Natural Sciences -- academic theses", "Middlesex College (Edison, NJ) -- Student works", "Middlesex County College (Edison, NJ)" ] } }, { "label": { "en": [ "Temporal Coverage" ] }, "value": { "none": [ "Academic Year 2015-2016 ( 2015 - 2016 )" ] } }, { "label": { "en": [ "Title" ] }, "value": { "none": [ "Amine-Catalyzed Direct Asymmetric Mannich Reaction" ] } }, { "label": { "en": [ "Series Title" ] }, "value": { "none": [ "Student Symposium 2015" ] } }, { "label": { "en": [ "Format" ] }, "value": { "none": [ "Mixed Material" ] } }, { "label": { "en": [ "Digital Resource Creation Date" ] }, "value": { "none": [ "6/22/2021" ] } } ], "service": [ { "@context": "http://iiif.io/api/search/2/context.json", "id": "https://digital.middlesexcollege.edu/iiif/manifest/AA00002430/00001/search", "type": "SearchService2", "profile": "http://iiif.io/api/search/2/search" } ], "seeAlso": [ { "id": "https://digital.middlesexcc.edu/content/AA/00/00/24/30/00001/AA00002430_00001.mets.xml", "type": "Dataset", "format": "application/mets\u002Bxml", "label": { "en": "METS" } }, { "id": "https://digital.middlesexcc.edu/content/AA/00/00/24/30/00001/marc.xml", "type": "Dataset", "format": "application/marcxml\u002Bxml", "label": { "en": "MARCXML" } } ], "items": [] }