{ "@context": "http://iiif.io/api/presentation/3/context.json", "id": "https://digital.middlesexcollege.edu/iiif/manifest/AA00002440/00001", "type": "Manifest", "label": { "none": [ "New Methodology Attempted for the Synthesis of Chloramphenicol" ] }, "metadata": [ { "label": { "en": [ "Abstract" ] }, "value": { "none": [ "A new synthetic method for preparation of the antibiotic drug, Chloramphenicol, was proposed. The earlier methods of producing the drug involves utilization of hazardous chemicals. The motive was to find a synthesis method was to utilize as much as non-hazardous materials to prepare the drug. The goal was to optimize the conditions for the adoptions of the methodology in industrial scale. The hypothesis involved using enantioselective catalysts- Diphenyl Prolinol for Michael addition of p-Nitrobenzaldehyde and the amino group. The hypothesis suggests a yield of over 90% of the desired isomer. The Aminodiacetylaldehyde dimethyl acetal was first reacted with Dichloroactyl chloride. The product was then deprotected and further reacted with p-Nitrobenzaldehyde in the presence of the catalyst. Further the desired isomer was reduced with Sodium Borohydride. The expected product obtained would be cis isomer of the required molecule. Further, the molecule would be tested for its antibiotic properties." ] } }, { "label": { "en": [ "Publication Date" ] }, "value": { "none": [ "2018" ] } }, { "label": { "en": [ "Hierarchical Spatial" ] }, "value": { "none": [ "New Jersey -- Edison" ] } }, { "label": { "en": [ "Holding Location" ] }, "value": { "none": [ "Middlesex County College Institution" ] } }, { "label": { "en": [ "Permanent Link" ] }, "value": { "none": [ "http://middlesexcc.sobeklibrary.com/AA00002440/00001" ] } }, { "label": { "en": [ "Creator" ] }, "value": { "none": [ "Bagga, Surleen Singh", "Ghosh, Phalguni", "Middlesex College, Department of Natural Sciences", "Lavey, Brian" ] } }, { "label": { "en": [ "Publisher" ] }, "value": { "none": [ "Middlesex College" ] } }, { "label": { "en": [ "Place of Publication" ] }, "value": { "none": [ "Edison, NJ" ] } }, { "label": { "en": [ "Type" ] }, "value": { "none": [ "Mixed Material" ] } }, { "label": { "en": [ "Source Institution" ] }, "value": { "none": [ "Middlesex County College Institution" ] } }, { "label": { "en": [ "Subjects / Keywords" ] }, "value": { "none": [ "College students -- poster presentations", "Student Works -- Natural Sciences -- poster presentations", "Chemistry", "Student works -- Natural Sciences -- academic theses", "Middlesex College (Edison, NJ) -- Student works", "Middlesex County College (Edison, NJ)" ] } }, { "label": { "en": [ "Temporal Coverage" ] }, "value": { "none": [ "Academic Year 2018-2019 ( 2018 - 2019 )" ] } }, { "label": { "en": [ "Title" ] }, "value": { "none": [ "New Methodology Attempted for the Synthesis of Chloramphenicol" ] } }, { "label": { "en": [ "Series Title" ] }, "value": { "none": [ "Student Symposium 2018" ] } }, { "label": { "en": [ "Format" ] }, "value": { "none": [ "Mixed Material" ] } }, { "label": { "en": [ "Digital Resource Creation Date" ] }, "value": { "none": [ "6/30/2021" ] } } ], "service": [ { "@context": "http://iiif.io/api/search/2/context.json", "id": "https://digital.middlesexcollege.edu/iiif/manifest/AA00002440/00001/search", "type": "SearchService2", "profile": "http://iiif.io/api/search/2/search" } ], "seeAlso": [ { "id": "https://digital.middlesexcc.edu/content/AA/00/00/24/40/00001/AA00002440_00001.mets.xml", "type": "Dataset", "format": "application/mets\u002Bxml", "label": { "en": "METS" } }, { "id": "https://digital.middlesexcc.edu/content/AA/00/00/24/40/00001/marc.xml", "type": "Dataset", "format": "application/marcxml\u002Bxml", "label": { "en": "MARCXML" } } ], "items": [] }