The Synthesis of 8-Hydroxyquinoline-7-Carbaldehyde Schiff-Base as a Fluorescence Chemosensor for Al3+

Material Information

Title:
The Synthesis of 8-Hydroxyquinoline-7-Carbaldehyde Schiff-Base as a Fluorescence Chemosensor for Al3+
Series Title:
Student Symposium 2019
Creator:
Harding, Glenn ( Author, Primary )
Middlesex College -- Department of Natural Sciences
Ghosh, Phalguni ( Advisor )
Place of Publication:
Edison, NJ
Publisher:
Middlesex College, Department of Natural Sciences
Publication Date:
Physical Location:
Middlesex County College Board of Trustees Meeting Materials Box
Folder

Subjects

Subjects / Keywords:
Middlesex County College (Edison, N.J.) ( lcsh )
Biochemistry ( lcsh )
Molecular Biology ( lcsh )
Middlesex College -- Student Works -- poster presentations
College students -- poster presentations ( lcsh )
Temporal Coverage:
Academic Year 2019-2020 ( 2019 - 2020 )
Spatial Coverage:
NJ -- Middlesex County -- Edison

Notes

Abstract:
For this project, we attempted to synthesize and study the activity of the 4-(8’- hydroxyquinolin-7’-yl)methyleneimino-1-phenyl-2,3-dimethyl-5-pyzole (HQ7A sensor) with several metal ion, including Al3+ using UV visible spectroscopy and fluorescent studies. First, 8- Hydroxyquinoline has to undergo a Reimer-Tiemann reaction by being refluxed for 12 hours with chloroform and sodium hydroxide in ethanol. Then distill of excess chloroform and ethanol, acidified with hydrochloric acid, extracted with chloroform, and separated through column chromatography. Then, having the 8-Hydroxyquinoline-7-Carbaldehyde (HQ7A) isolated, refluxing it with a 1:1 mol ratio of 4-aminoantipyrine in ethanol for 8 hours. After the 8 hour reflux, a yellow precipitate falls out of solution and has to be separated by vacuum filtration. After forming the sensor, the isosbestic points are found by testing absorbance, the intensity of fluorescence is measured against different ions, and the intensity of the fluorescence is measured with the addition of aluminum

Record Information

Source Institution:
Middlesex County College
Holding Location:
Middlesex County College
Rights Management:
All rights reserved by the source institution.