Designing Drug-Like Molecules using Bioinformatics

Material Information

Title:
Designing Drug-Like Molecules using Bioinformatics
Series Title:
Student Symposium 2016
Creator:
Ghigliotty, Natalie ( Author, Primary )
Ghosh, Phalguni ( Advisor )
Middlesex College, Department of Natural Sciences ( Sponsor )
Place of Publication:
Edison, NJ
Publisher:
Middlesex College
Publication Date:

Subjects

Subjects / Keywords:
College students -- poster presentations ( lcsh )
Student Works -- Natural Sciences -- poster presentations ( lcsh )
Chemistry ( lcsh )
Biochemistry ( lcsh )
Middlesex College (Edison, NJ) -- Student works
Middlesex County College (Edison, NJ) ( lcsh )
Temporal Coverage:
Academic Year 2016-2017 ( 2016 - 2017 )
Spatial Coverage:
New Jersey -- Edison

Notes

Abstract:
Abstract:The Drug Discovery process is a very time consuming, expensive process. It may take one-billion dollars and twenty years to bring a drug to market and making it available for people to use. Any approach that can be found to cut down on the time and money spent during the drug discovery process is valuable. The goal of this research was to build inhibitors for the human protein, Dipeptidyl Peptidase IV, also known as DPP4. DPP4 is a protein found in humans that is responsible for problems related to Type-2 diabetes. The goal here was not only to build inhibitor of this protein, but to create entirely new molecules that have never been tested in DPP4 to our knowledge before. This research is open-ended, meaning that someone may pick up where we left off and attempt to synthesize these molecules in the lab, and eventually test them in DPP4 for their inhibition activity. This research is valuable, there is a great deal of people around the world today struggling with Diabetes, so any way we are able to improve on research and development that is being done today is useful.

Record Information

Source Institution:
Middlesex County College Institution
Holding Location:
Middlesex County College Institution
Rights Management:
All applicable rights reserved by the source institution and holding location.

MCC Membership

Aggregations:
Middlesex College
Student Symposium
Student Works