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Cannabinoid 1 ReceptorInteraction: Distinguishing an Agonist vs Antagonist
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Open-NJ Link:
http://middlesexcc.sobeklibrary.com/AA00002422/00001
Material Information
Title:
Cannabinoid 1 ReceptorInteraction: Distinguishing an Agonist vs Antagonist
Series Title:
Student Symposium 2017
Creator:
Alb, Josh
(
Author, Primary
)
Ghosh, Phalguni
(
Advisor
)
Lavey, Brian
(
Advisor
)
Ghosh, Sutapa
(
Advisor
)
Middlesex College, Department of Natural Sciences
(
Sponsor
)
Place of Publication:
Edison, NJ
Publisher:
Middlesex College
Publication Date:
2017
Subjects
Subjects / Keywords:
College students -- poster presentations
( lcsh )
Student Works -- Natural Sciences -- poster presentations
( lcsh )
Chemistry
( lcsh )
Biochemistry
( lcsh )
Middlesex College (Edison, NJ) -- Student works
Middlesex County College (Edison, NJ)
( lcsh )
Student Works -- Natural Sciences -- academic theses
Temporal Coverage:
Academic Year 2017-2018 ( 2017 - 2018 )
Spatial Coverage:
New Jersey -- Edison
Notes
Abstract:
Cannabinoids have shown the capacity and ability to treat numerous diseases andailments such as pain[1], grand mal epileptic seizures[2], anxiety[3], and migraines[4]. Cannabinoidsinteract with known cannabinoid receptor sites labeled cannabinoid 1 (CB1) receptor andcannabinoid 2 (CB2 receptor)[5]. These cannabinoids can function as either an agonist, inverseagonist, or antagonist. Although their function is known the reason why cannabinoids bind aseither an agonist or antagonist is not. The goal of this research is to analyze how agonist bindingcannabinoids and antagonist binding cannabinoids interact with the CB1 receptor site, whichamino acid residues they share, and which amino acid residues differ. This information will helpus determine why cannabinoids induce different effects on their consumer and how we mayexamine the key residue interaction to determine how to construct better cannabinoids anddetermine how an unknown cannabinoid will function.
Record Information
Source Institution:
Middlesex County College Institution
Holding Location:
Middlesex County College Institution
Rights Management:
All applicable rights reserved by the source institution and holding location.
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