Asymmetric Michael Addition Catalyzed by a Chiral Polystyrene-Immobilized Pyrrolidine

Material Information

Title:
Asymmetric Michael Addition Catalyzed by a Chiral Polystyrene-Immobilized Pyrrolidine
Series Title:
Student Symposium 2013
Creator:
Schneier, Andrew ( Author, Primary )
Ghosh, Phalguni ( Advisor )
Middlesex College, Department of Natural Sciences ( Sponsor )
Place of Publication:
Edison, NJ
Publisher:
Middlesex College
Publication Date:

Subjects

Subjects / Keywords:
College students -- poster presentations ( lcsh )
Student Works -- Natural Sciences -- poster presentations ( lcsh )
Chemistry ( lcsh )
Student works -- Natural Sciences -- academic theses ( lcsh )
Middlesex College (Edison, NJ) -- Student works
Middlesex County College (Edison, NJ) ( lcsh )
Temporal Coverage:
Academic Year 2013-2014 ( 2013 - 2914 )
Spatial Coverage:
New Jersey -- Edison

Notes

Abstract:
Polystyrene-immobilized pyrrolidine has been synthesized using Merrifieldresin to attach propargyl alcohol via a SN2 mechanism. The Terminal alkyne then reacts with an organic azide through a click 1,3-cycloaddtion to produce a chiral organocatalyst. The organocatalyst is synthesized to give high yield (u pto 99%), and stereoselectivity (up to 99% ee) of a Michael addition reaction between cyclohexanone and nitrostyrene.
Preferred Citation:
Schneier, A. Asymmetric Michael Addition Catalyzed by a Chiral Polystyrene-Immobilized Pyrrolidine; MCC Student Symposium 2013; Middlesex County College: Edison, NJ, 2013. http://middlesexcc.sobeklibrary.com/AA00002436/00001

Record Information

Source Institution:
Middlesex County College Institution
Holding Location:
Middlesex County College Institution
Rights Management:
All applicable rights reserved by the source institution and holding location.

MCC Membership

Aggregations:
Middlesex College
Student Symposium
Student Works