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001        AA00002440_00001
005        20230118092611.0
006        m^^^^^o^^^^^^^^^^^
007        cr^^n^---ma^mp
008        210630n^^^^^^^^xx^^^^^^s^^^^^^^^^^^eng^d
245 00 |a New Methodology Attempted for the Synthesis of Chloramphenicol |h [electronic resource].
260        |a Edison, NJ : |b Middlesex College, |c 2018.
490        |a Student Symposium 2018.
520 3    |a A new synthetic method for preparation of the antibiotic drug, Chloramphenicol, was proposed. The earlier methods of producing the drug involves utilization of hazardous chemicals. The motive was to find a synthesis method was to utilize as much as non-hazardous materials to prepare the drug. The goal was to optimize the conditions for the adoptions of the methodology in industrial scale. The hypothesis involved using enantioselective catalysts- Diphenyl Prolinol for Michael addition of p-Nitrobenzaldehyde and the amino group. The hypothesis suggests a yield of over 90% of the desired isomer. The Aminodiacetylaldehyde dimethyl acetal was first reacted with Dichloroactyl chloride. The product was then deprotected and further reacted with p-Nitrobenzaldehyde in the presence of the catalyst. Further the desired isomer was reduced with Sodium Borohydride. The expected product obtained would be cis isomer of the required molecule. Further, the molecule would be tested for its antibiotic properties.
533        |a Electronic reproduction. |c Middlesex County College Institution, |d 2021. |f (Middlesex County College) |n Mode of access: World Wide Web. |n System requirements: Internet connectivity; Web browser software.
535 1    |a Middlesex County College Institution.
648        |a 2018-2019 |y Academic Year 2018-2019.
650    0 |a College students -- poster presentations.
650    0 |a Student Works -- Natural Sciences -- poster presentations.
650    0 |a Chemistry.
650    0 |a Student works -- Natural Sciences -- academic theses.
650        |a Middlesex College (Edison, NJ) -- Student works.
650    0 |a Middlesex County College (Edison, NJ).
700 1    |a Bagga, Surleen Singh, |e author, primary.
700 1    |a Ghosh, Phalguni. |4 ths
700        |a Middlesex College, Department of Natural Sciences. |4 spn
700 1    |a Lavey, Brian. |4 ths
830    0 |a Middlesex County College.
830    0 |a Student Symposium.
830    0 |a Student Works.
852        |a MCC |c Student Symposium
856 40 |u http://middlesexcc.sobeklibrary.com/AA00002440/00001 |y Electronic Resource
992 04 |a https:/digital.middlesexcc.edu/content/AA/00/00/24/40/00001/Thesis-Surleen Singh Bagga-Synthetic Chem_ 2018pdfthm.jpg
997        |a Student Symposium


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